Abstract: A new topically active non-steroidal antiandrogen, RU 58841 has been synthesized. It displays high affinity for the hamster prostate […]

Abstract: The effect of androgen receptor transcriptional activation by RU58841, a nonsteroidal anti-androgen, was studied in the human prostate cancer […]

Abstract: TZP-4238 is a new potent, orally active steroidal antiandrogen. Antiandrogenic activity and endocrinological profile of TZP-4238 were investigated in […]

Abstract: Turosteride was tested in a series of studies for its effect on 5 alpha-reductase and for its possible influence […]

Abstract: Turosteride [FCE 26073; 1-(4-methyl-3-oxo-4-aza-5 alpha-androstane-17 beta-carbonyl)-1,3- diisopropylurea] is a novel inhibitor of 5 alpha-reductase, the enzyme responsible for the […]

In an article posted to alt.baldspot, it is confirmed that Merck’s research drug, MK-386, is currently being tested for hair […]

Abstract: TZP-4238, a new steroidal antiandrogen, is an orally active drug in rats and dogs. The effects of TZP-4238 on […]

Abstract: Using chlormadiNone acetate (CMA) as the control drug, a double-blind study was carried out to examine not only the […]

Abstract: Steroid 5alpha-reductase is required for the conversion of testosterone to dihydrotestosterone. Localization of type 1 5alpha-reductase in the sebaceous […]

Abstract: Abstract not available online.   Author: Bakshi RK; Patel GF; Rasmusson GH; Baginsky WF; Cimis G; Ellsworth K; Chang […]