Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men

Abstract: Two isozymes (types 1 and 2) of 5 alpha-reductase (5 alpha R; EC 1.3.99.5), with differential tissue distribution, have […]

A parathyroid hormone antagonist stimulates epidermal proliferation and hair growth in mice

Abstract: The biologic action of parathyroid hormone (PTH)-related peptide (PTHrP) in normal skin was investigated in cultured human keratinocytes and in SKH-1 […]

Hair Loss Study Abstract: Control of Hair Growth with Parathyroid Hormone-Part V

  Figure 4. Histomorphometric analysis of the hair follicles from the back skin of control and PTH (7-34)-treated mice on […]

Overexpression of parathyroid hormone-related protein in the skin of transgenic mice interferes with hair follicle development

Abstract: Parathyroid hormone-related peptide (PTHrP) was initially discovered as the cause of the syndrome of humoral hypercalcemia of malignancy. Subsequently, the […]

Novel aromatase and 5 alpha-reductase inhibitors

Abstract: Inhibitors of aromatase and 5 alpha-reductase may be of use for the therapy of postmenopausal breast cancer and benign […]

FK143, a novel nonsteroidal inhibitor of steroid 5 alpha-reductase: (1) In vitro

Abstract: Steroid 5 alpha-reductase is an enzyme which converts testosterone into 5 alpha-dihydrotestosterone (DHT) and is implicated in the pathogenesis […]

Novel steroid 5 alpha-reductase inhibitor FK143

Abstract: Recent cloning of the cDNAs for the two isozymes of steroid 5 alpha-reductase (EC 1.3.99.5) allowed individual expression of […]

Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer

Abstract: Tamoxifen, a nonsteroidal estrogen antagonist, is the most prescribed drug for the treatment of breast cancer. The use of […]

Hair Loss Study Abstract: Control of Hair Growth with Parathyroid Hormone-Part IV

  Figure 2. Effect ofPTH (7-34) on the hair cycle stage represented by macroscopic evaluation of percent area of back […]

Estrogen Blocker Grows Hair

Researchers say a compound used in laboratory experiments to block the production of estrogen also has the surprising side effect […]
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