Reversal of androgenic alopecia by minoxidil: lack of effect of simultaneously administered intermediate doses of cyproterone acetate

Abstract: A male volunteer with frontal alopecia was treated simultaneously with 20 mg cyproterone acetate and 5 mg minoxidil topically […]

Efficacy of low-dose GnRH analogue (Buserelin) in the treatment of hirsutism

Abstract: The aim of the present study was to evaluate the effect of low dose GnRH analogue (Buserelin) on gonadal steroid secretion […]

Treatment of hirsutism, acne and alopecia with cyproterone acetate

Abstract: Cyproterone acetate, combined with ethinyl estradiol, was administered to 60 women (mean age: 25 years) suffering from hirsutism, acne […]

Sequential estrogen-progestin addition to gonadotropin-releasing hormone agonist suppression for the chronic treatment of ovarian hyperandrogenism

Abstract: The purpose of the study was to evaluate the efficacy and safety of a sequential regimen of estrogen-progestin addition […]

Clinical and hormonal effects of chronic gonadotropin-releasing hormone agonist treatment in polycystic ovarian disease

Abstract: Previously, we reported that short term administration of a highly potent GnRH agonist (GnRHa) for 1 month to patients […]

“Casodex” (ICI 176,334)–a new, pure, peripherally-selective anti-androgen: preclinical studies

Abstract: The relative merits of the steroidal anti-androgen, cyproterone acetate, and the non-steroidal anti-androgens flutamide and nilutamide, are reviewed. It […]

A double-blind controlled evaluation of the sebosuppressive activity of topical erythromycin-zinc complex

Abstract: In a double-blind randomized study, 14 volunteers applied 4% erythromycin plus 1.2% zinc (Zineryt lotion) and 4% erythromycin lotions, each on […]

Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid

Abstract: The effects of zinc sulphate and azelaic acid on 5 alpha-reductase activity in human skin were studied using an in vitro […]

Effect of a topical erythromycin-zinc formulation on sebum delivery. Evaluation by combined photometric-multi-step samplings with Sebutape

Abstract: Zinc displays ‘in vitro’ some antiandrogen activity through an inhibition of the 5 alpha-reductase activity. The clinical relevance of […]

Spironolactone directly inhibits proliferation of cultured human facial sebocytes and acts antagonistically to testosterone and 5 alpha-dihydrotestosterone in vitro

Abstract: Spironolactone produces antiacne effects and has recently been shown to inhibit 5 alpha-dihydrotestosterone (5 alpha-DHT) receptors in human sebaceous […]
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