Antiandrogens in monotherapy or combined therapy for treatment of advanced cancer of the prostate

Abstract: This study undertaken on antiandrogens alone or in combination for treatment of prostate cancer shows the efficacy of flutamide in advanced […]

Effects of flutamide, a pure antiandrogen, on endocrine parameters, in the adult female rat

Abstract: Since antiandrogens having mixed agonistic-antagonistic activities on the androgen receptor have shown benefits in the treatment of hirsutism, the […]

Inocoterone and acne. The effect of a topical antiandrogen: results of a multicenter clinical trial

Abstract: BACKGROUND AND METHODS–Because acne is androgen dependent, antiandrogen therapy might improve the condition. Inocoterone acetate (RU 882) is a […]

Induction of anagen in telogen mouse skin by topical application of FK506, a potent immunosuppressant

Abstract: The effect of topical application of FK506 on the normal hair cycle of C57BL/6J mice was investigated. When telogen […]

Effect of finasteride, a 5 alpha-reductase inhibitor on prostate tissue androgens and prostate-specific antigen

Abstract: Whole tissue dihydrotestosterone (DHT) and testosterone (T) concentrations have been measured after finasteride, a 5 alpha-reductase inhibitor, and this […]

Proscar: five-year experience

Abstract: We assessed the long-term safety and efficacy of finasteride, an orally active 5 alpha-reductase inhibitor, in 2 previously reported […]

Finasteride inhibits 5 alpha-reductase activity in human dermal fibroblasts: prediction of its therapeutic application in androgen-related skin diseases

Abstract: BACKGROUND. The potential role of finasteride in treating androgen related skin disorders was investigated. METHODS. Pooled human dermal fibroblasts […]

Local and systemic reduction by topical finasteride or flutamide of hamster flank organ size and enzyme activity

Abstract: The hamster flank organ is a widely used model of the control of sebaceous gland activity by androgens and […]

Sports Stars Could Help New Hair Trend Grow in Popularity

CHICAGO, /PRNewswire/ — Utah Jazz superstar Karl Malone and Green Bay Packers’ head football coach Mike Holmgren were introduced at […]

Enhanced in vitro hair growth at the air-liquid interface: minoxidil preserves the root sheath in cultured whisker follicles

Abstract: Inasmuch as hair follicles are difficult to maintain in culture, the study of hair biology using cultured hair follicles […]
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