Longevity drugs · other

Taurine

An amino acid that declines with age; extended lifespan in mice, human trials pending.

GRADE D· Mostly preclinicalSupplement$10–$25 / mo

Not medical advice — talk to a licensed clinician. Content is educational, reflects published literature, and is not a recommendation to start, stop or change any treatment.

What it is

A conditionally essential amino acid found in meat, fish and many energy drinks.

How it works, in plain English

Supports mitochondrial function, bile acid formation and cellular stress responses.

What the human evidence shows

A 2023 Science paper reported blood taurine declines with age and supplementation extended mouse lifespan 10–12%. Human aging data is observational.

Regrowth grade D: Mostly preclinical.

Typical protocols in the literature

The literature references 1–6 g/day in human studies of other conditions.

Described for education, not as dosing advice.

Side effects & interactions

Side effects

  • Generally well tolerated
  • Possible GI upset

Interactions

  • May modestly lower blood pressure

Key studies

  • Singh et al. 2023, Science — taurine deficiency as a driver of aging

Citations pending medical review